Just a few years ago, cannabis was considered the “final frontier” of decriminalization. The progress in this area was swift and sweeping, but as it turns out cannabis legalization was just the beginning. The real final frontier is psychedelic drugs, and the regulatory barriers are being broken down one by one.

Unlike with cannabis, psychedelic medicine isn’t a mature market yet. You can drive down the street or look online and find cannabis dispensaries, but the psychedelics market remains largely untapped simply because of regulatory hurdles.

The ultimate hurdle, a milestone that the psychedelics market can look forward to, will be getting these medicines off of Schedule I classification in the United States.

As we witnessed with cannabis, Canada is leading the way in working towards national declassification and decriminalization of psychedelic medicines.

The final quarter of 2020 was a challenging time due to a resurgence of the Covid-19 pandemic, along with a particularly divisive election cycle in the U.S. Yet, this was also a time when laws and regulations evolved to reflect the citizens’ shifting sentiment towards psychedelic medicines.

The groundswell of support could be traced back to August of 2020, when over 13,000 Canadians signed a petition to legalize natural psychedelic drugs in Canada. The petition correctly asserted that “In the midst of an overdose crisis, accompanied by the causes of trauma, anxiety and depression, a wider range of treatment modalities, including those informed by ancient and indigenous knowledge, are urgently needed.”

Courtesy: hhs.gov

Without a doubt, the “overdose crisis” they’re referring to includes opioid addiction, which is a pervasive problem in North America. Approximately 2.1 million Americans have an opioid use disorder, and tragically, around 130 Americans die every day from an opioid overdose.

Plus, a few years ago, a government-sanctioned study found that an estimated 21 million people aged 12 or older needed substance use treatment. That’s around 1 in 13 people, or 7.8% of the population, in that age bracket in need of treatment for substance use.

In order to further its objective of developing leading-edge psychedelic medicines to treat addiction, Entheon Biomedical has embarked on a number of value-added partnerships. Just recently the company revealed that it entered into a Clinical Study Agreement with the Contract Research Organization (CRO) Centre for Human Drug Research (CHDR) to conduct an early phase human clinical trial with DMT.

With this collaboration, Entheon has contracted CHDR to carry out a controlled, data-intensive study to evaluate the pharmacodynamics, pharmacokinetics, and safety of a target-controlled intravenous infusion of DMT in humans.

“With the CHDR’s partner pharmacy having successfully received an amendment to its opioid license to include DMT and having applied for its import permit for DMT, we are advancing on steps for our clinical trial, which is expected to start in the late summer of 2021,” commented Mr. Ko.

Entheon has also announced a strategic investment in Wonder Scientific Inc., whose team of University Researchers and Product Development experts create custom, naturally derived, active pharmaceutical ingredients (APIs) to supply the growing global clinical and commercial demand for psychedelics.

The investment in Wonder Scientific will provide exposure in other verticals of the psychedelic therapy space and strategic access to psychoactive pharmaceutical ingredients and scientific bench strength as Entheon develops therapeutic treatments for addiction.

On top of that, Entheon has entered into a value-added DMT supply agreement with Psygen Labs Inc. Timothy Ko explains, “Partnering with Canada’s first licensed manufacturer of restricted psychedelic drug products fosters an ecosystem of collaboration and innovation within the Canadian psychedelic space, and we are thrilled by the progress being made.”

Entheon’s mandate is two-fold: to make money, yes, but also to help people. The company exists in a highly opportune space with the potential to provide a high-need service for an as-yet unaddressed market. If you’re interested in an investment that can provide wealth while also changing lives for the better, then Entheon should absolutely be on your radar.

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